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Fu-Giles, Patty


Assistant Professor of Chemistry
Division: Science
Program: Chemistry
Office: F1677
Phone: 708.235.7343


Education | Publications | Honors | Presentations | Service | Professional Memberships

Education

  • Ph.D., Chemistry, The Ohio State University, Columbus, OH. 2001
  • M.S., Chemistry, The Ohio State University, Columbus, OH, 1998
  • M.S., Environmental Biology, Governors State University, University Park, IL, 1995
  • B.S., Microbiology, Western Illinois University, Macomb, IL, 1985

Publications

  • "Ground State and Excited State Properties of New Complexes of Ru(II) with Oxtgen Coordination”, P. K.-L. Fu, D. L. Lutterman, L. A. Lazinski-Melanson, Y. Asher, D. H. Johnston, and C. Turro, Manuscript in preparation.
  • "Photoinduced Damage to Human Skin Fibroplasts by a Quinone Diimine Complex of  Zinc(II): Plasmid Linearization, Nuclear DNA Cleavage, and Cell Death", Patty K.-L. Fu, Christopher L. Dollberg, and Claudia Turro, Biol. Inorg. Chem. Manuscript submitted for publication.
  • "Dirhodium (II,II) Complexes: Molecular Characteristics that Affect in Vitro Activity”, A. M. Angeles-Boza, H. T. Chifotides, J. D. Aguirre, A, Chouai, P. K.-L. Fu, K.R. Dumber, and C. Turro, J. Med. Chem. 2006, 49, 6841-6847.
  • "cis-[Rh2(-O2CCH3)2(CH3CN)6]2+ as a Photo-Activated Cisplatin Analog”, Deniel A. Lutterman, Patty K.-L. Fu, and Claudia Turro, J. Am. Chem. Soc.; 2006, 128, 738-739.
  • "Photocytotoxicity of a New Rh2(II/II) Complex:  Increase in Cytotoxicity upon Irradiation Similar to PDT Agent Hematoporphyrin”, Alfredo M. Angeles-Boza, Patricia M. Bradley,  Patty K.-L. Fu, Kim R. Dunbar, and Claudia Turro, Inorg Chem. 2005, 44(21), 7262-4.
  • "Photoinduced DNA Cleavage and Cellular Damage in Human Dermal Fibroblasts by 2,3-Diaminophenazine", Patty K.-L. Fu, Sonia Abuzakhm and Claudia Turro, Photochem. Photobiol. 2005, 81(1), 89-95.
  • "DNA Binding and Photocleavage in vitro by New Dppz Dirhodium(II/II) Complexes:  Correlation to Cytotoxicity and Photocytotoxicity", Alfredo M. Angeles-Boza, Patricia M. Bradley, Patty K.-L. Fu, Sara E. Wicke, John Bacsa, Kim R. Dunbar and Claudia Turro, Inorg. Chem. 2004, 43(26), 8510 -8519.
  • "Profound Effect of Bridging Ligands of Dirhodium(II) Complexes on the Efficiency and Mechanism of Transcription Inhibition in Vitro", Helen T. Chifotides, Patty K.-L. Fu, Kim R. Dunbar, and Claudia Turro, Inorg. Chem. 2004, 43, 1175-1183.
  • "Stabilization of Duplex DNA Structure and Suppression of Transcription in Vitro by Bis(quinone diimine) Complexes of Rhodium(III) and Ruthenium(II)", Patty K.-L. Fu, Patricia M. Bradley, and Claudia Turro, Inorg. Chem.; 2003; 42(3); 878-884.
  • "Inhibition of Transcription in Vitro by Anticancer Active Dirhodium(II) Complexes", K. Sorasaenee, P. K.-L. Fu, A. M. Angeles-Boza, K. R. Dunbar, and C. Turro, Inorg. Chem.; 2003; 42(4); 1267-1271.
  • "Lanthanide Ions as Luminescent Probes of Proteins and Nucleic Acids" Claudia Turro, Patty K.-L. Fu and Patricia M Bradley, "The Lanthanides and Their Interrelations with Biosystems", Vol. 40 of Met. Ions Biol. Syst., Sigel A.; Sigel, H., Eds., M. Dekker: New York, 2003, 323¬-349.
  • "DNA Photocleavage by a Supermolecular Ru(II)-Viologen Complex",  P. K.-L. Fu, P. M. Bradley, D. van Loyen, H. Durr, S. H. Bossmann, and C. Turro, Inorg. Chem.; 2002; 41 (15); 3808-3810
  • "DNA Cleavage by Photogenerated Rh2(O2CCH3)4(H2O)2+",  Patty K.-L. Fu, Patricia M Bradley, and Claudia Turro, Inorg. Chem.; 2001; 40(11); 2476-2477.
  • "Solution Chemistry and DNA Cleavage by Photogenerated Rh2(O2CCH2)4+", Patricia M. Bradley, Patty K.-L. Fu and Claudia Turro, Spectrum 2001, 14, 12¬-16.
  • "Excited State Properties of Rh2(O2CCH3)4: Solution Photochemistry and Photoinduced DNA Cleavage", Patricia M. Bradley, Patty K.-L. Fu, and Claudia Turro, Comments on Inorg. Chem. 2001, 22, 393-426.
  • "Transcription Inhibition by Rh(phi)2phen3+", Patty K.-L. Fu and Claudia Turro, Chem. Comm. 2001, 279-280.
  • "Energy Transfer from Nucleic Acids to Tb(III): Selective Emission Enhancement by Single DNA Mismatches", Patty K.-L.Fu. and Claudia Turro, J. Am. Chem. Soc.; 1999; 121(1); 1-7. 

Honors

  • 2005     Quality Performance Award, CFSAN, FDA
  • 2004     Quality Performance Award, CFSAN, FDA
  • 2003     Quality Performance Award, CFSAN, FDA
  • 2001     CIC Women in Science Competitive Travel Grant, Eli Lilly Corporation
  • 2000     Second Place, Evans Lecture Poster Competition; The Ohio State University
  • 1998     Second Place, Evans Lecture Poster Competition; The Ohio State University
  • 1995     Alumni Competitive Scholarship Award, Governors State University
  • 1994     Alumni Competitive Scholarship Award, Governors State University

Presentations

  • Poster presentation at 35th Great Lakes meeting of American Chemical Society, Chicago, IL, 2009.
  • Poster presentation at the 108th National meeting of American Society of Microbiology, Boston, MA, 2008.
  • Poster presentation at the Advanced Technology Application for Combat   Casualty Care. Tampa, FL, 2008.
  • Poster presentation at the Advanced Technology Application for Combat   Casualty Care. Tampa, FL, 2007.
  • Oral presentation at 85th International Association of Dental Research, New Orleans, Louisiana, 2007.
  • Special Departmental Seminar, Department of Chemistry, Ohio University, Athens, OH, 2006.
  • Poster presentation at 12th Annual FDA Science Forum in Washington, D.C, 2006
  • Poster presentation at the 230th ACS National Meeting, August 2005, Washington, D.C, 2005
  • Poster presentation at the 229th ACS National meeting, March 2005, San Diego, CA, 2005
  • Special Departmental Seminar, Department of Chemistry, University of Nebraska-Lincoln, Nebraska, 2005
  • Poster presentation at 11th Annual FDA Science Forum in Washington, D.C., 2005
  • Poster presentation at 10th Annual FDA Science Forum in Washington, D.C.,2004
  • Oral presentation at FDA- Office of Cosmetic and Colors brown bag seminar, College Park, Maryland, 2004
  • Poster presentation at Photochemistry Gordon Research Conference in South Hadley, MA, 2003
  • Poster presentation at American Society of Photobiology National Meeting in Baltimore, MD, 2003
  • Oral presentation at JPL (Jet Propulsion Laboratory) in Pasadena, CA, 2002
  • Oral presentation at American Chemical Society National Meeting in San Diego, CA, 2001
  • Oral presentation at American Chemical Society Central Regional Meeting in Cincinnati, OH, 2000
  • Oral presentation at American Chemical Society National Meeting in   Washington, DC, 2000
  • Poster presentation at Frontiers of Science Symposium; National Academy of Science, Irvine, California, 2000
  • Poster presentation at American Chemical Society Central Regional Meeting in Columbus, OH, 1999
  • Oral presentation at American Chemical Society National Meeting in Boston, MA, 1998

Service

  • Elected and served as a member in the Scientific Preventative Maintenance Committee to evaluate and budget the current service contracts (CFSAN – FDA).
  • Elected and served as a member in the Color Additive Petition Committee to evaluate and certify the permanent listing of colors for use in food (CFSAN– FDA).
  • Elected and served as the Management Control Review Coordinator (NIDBR – NAVY).
  • Elected and served as Vice – Chairperson of the NIDBR Institutional Review Board (IRB) for the human subject researches.

Professional Memberships

  • American Chemical Society
  • American Society for Photobiology
  • Inter-American Photochemical Society